Current Clinical Trials
Cardiac
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This is an international, multicenter, parallel-group, randomized, double-blind,
placebo-controlled trial in patients who have been stabilized during hospitalization
for acute heart failure, evaluating the effect of in-hospital initiation
of dapagliflozin versus placebo on the clinical outcome of cardiovascular
death or worsening heart failure.
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A Randomized, Double-blind, Placebo-controlled Trial Assessing the Impact
of Inclisiran on Major Adverse Cardiovascular Events in Participants With
Established Cardiovascular Disease (VICTORION-2 PREVENT)
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A Randomized, Double-blind, Placebo-controlled Multicenter Study to Evaluate
the Effect of Inclisiran on Preventing Major Adverse Cardiovascular Events
in High-risk Primary Prevention Patients (VICTORION-1 PREVENT)
Gynecology
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Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial
Cancer, Ovarian Cancer, and Cervical Cancer
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STUDY ID:
ECHO
- Principal Investigator: Collette Lessard, MD
Oncology
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Blood
- A Post-authorization Safety Study to Evaluate the Incidence of and Risk
Factors for Severe and Fatal Infusion-related Reactions in Participants
Treated with Daratumumab (Intravenous or Subcutaneous)
- STUDY ID: HALO
- Principal Investigator: Karine Darbinyan, MD
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Breast
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TAILOR RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low-Risk
Node Positive and T3N0 Breast Cancer.
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Mepitel Film for the Reduction of Radiation Dermatitis in Breast Cancer
Patients Undergoing Post-Mastectomy Radiation Therapy: A Randomized Phase
III Clinical Trial
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Evaluation of Lasofoxifene Combine with Abemaciclib Compared with Fulvestrant
Combined with Abemaciclib in Locally Advanced or Metatstatic ER+/HR2-
Breast Cancer with an ESR1 Mutation
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STUDY ID:
ELAINE 3
- Principal Investigator: Grant Seeger, MD
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Kidney
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Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab
With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study.
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Lung
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This is a Phase III, randomized, placebo-controlled, double-blind, multi-center
study assessing the efficacy and safety of durvalumab with SoC SBRT versus
placebo with SoC SBRT in patients with unresected clinical Stage I/II
lymph node-negative (T1 to T3N0M0) NSCLC.
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MRI Brain Surveillance Alone Versus MRI Surveillance and Prophylactic Cranial
Irradiation (PCI): A Randomized Phase III Trial in Small-Cell Lung Cancer
(MAVERICK).
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Phase III Prospective Randomized Trial of Primary Lung Tumor Stereotactic
Body Radiation Therapy Followed by Concurrent Mediastinal Chemoradiation
for Locally Advanced Non-Small Cell Lung Cancer
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A Study of V940 Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab
in Participants with Non-Small Cell Lung Cancer
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STUDY ID:
V940-002
- Principal Investigator: Grant Seeger, MD
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Prostate
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This phase II trial compares the effect of oxybutynin versus placebo for
reducing hot flashes in men receiving androgen deprivation (hormone) therapy
for the treatment of prostate cancer. Androgen deprivation therapy decreases
testosterone and other androgens through medications or surgical removal
of the testicles. Relative to placebo, low- or high-dose oxybutynin may
reduce hot flashes in men receiving androgen deprivation therapy.
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Parallel Phase III Randomized Trials of Genomic-Risk Stratified Unfavorable
Intermediate Risk Prostate Cancer: De-Intensification and Intensification
Clinical Trial Evaluation (GUIDANCE).
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Parallel Phase III Randomized Trials for High Risk Prostate Cancer Evaluating
De-Intensification for Lower Genomic Risk and Intensification of Concurrent
Therapy for Higher Genomic Risk With Radiation (PREDICT-RT*)
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Relugolix Versus Leuprolide in Patients With Prostate Cancer: A Randomized,
Open-Label Study to Assess Major Adverse Cardiovascular Events (REPLACE-CV)
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Supportive Care
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A Randomized Phase III Trial of Olanzapine Versus Megestrol Acetate for
Cancer-Associated Anorexia.
Biorepository
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The Biorepository for Caris Life Sciences is designed for the purpose of
making quality biospecimens and associated clinical data available for
research studies related to advancing precision medicine and improving
care for patients.
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The Vallania Study: A Case Control Study for the Development of Multiomics
Blood Tests for Cancer Screening
You can
learn more about clinical trials by visiting clinicaltrials.gov, which is a database of privately and publicly funded clinical studies
conducted around the world.
Contact Us
Altru Health System, Research
1380 South Columbia Road
Grand Forks, ND 58201
Phone:
701.780.5195
Email:
adagoberg@altru.org