Michael Opoku-Darko

Michael Opoku-Darko, MD, MSc



Dr. Michael Opoku-Darko is a neurosurgeon at Altru Health System with special training in resection of “inoperable” brain tumors. He spent extra time with experts at the Mayo Clinic after his residency learning how to maximize the extent of removal of brain tumors while persevering neurological function. Outside of work, he enjoys music, playing soccer, and spending time with his family.

To schedule an appointment, please call 701.780.6427


Philosophy Of Medicine

"It’s a real privilege to be able to offer my expertise to some of the sickest and most vulnerable patients in medicine. I believe in establishing a strong surgeon-patient relationship to enhance proper assessment of the needs and expectations of each patient and their family before performing any surgical procedures."

Special Practices and Procedures

  • General Neurosurgery
  • Glioma
    • Biopsy
    • Surgical resection
    • Surgical resection with neuromonitoring
  • Meningioma
  • Metastatic brain tumor
  • Hydrocephalus
    • Shunts, Endoscopic 3rd ventriculostomy
  • Chiari malformation
  • Degenerative spine disease (Cervical and Lumbar)
    • MIS microdiscectomy
    • ACDF
    • Laminectomy
    • Fusions
  • Cavernous malformation
  • Arteriovenous Malformations
  • Pain/Functional neurosurgery
    • Trigeminal neuralgia
    • Carpal tunnel release
    • Hemifacial spasms


Formal Education

Jacobs University, Bremen, Germany, Bachelor of Science in Biochemistry and Cell Biology
University of Calgary, Alberta, Canada, Master of Science in Cancer Biology

Medical Education

University of Calgary, Alberta, Canada, Medical School


University of Calgary, Alberta, Canada, Neurosurgery


Mayo Clinic, Rochester, MN, Neurosurgical Oncology

Professional Memberships

  • Society for NeuroOncology (SNO)
  • Congress of Neurological Surgeons (CNS)
  • American Association of Neurological Surgeons (AANS)
  • Canadian Neurosurgical Society (CNSS)
  • Canadian Medical Association (CMA)



Natural History and Growth Patterns of Incidentally Discovered Diffusely Infiltrating Low-Grade Gliomas: A Volumetric Study.
Opoku-Darko M, Eagles ME, Cadieux M, Isaacs AM, Kelly JJP.
World Neurosurg. 2019 Dec;132:e133-e139.

Surgical Resection of Anterior and Posterior Butterfly Glioblastoma.
Opoku-Darko M, Amuah JE, Kelly JJP.
World Neurosurg. 2018 Feb;110:e612-e620.

Surgical management of incidentally discovered diffusely infiltrating low-grade glioma.
Opoku-Darko M, Lang ST, Artindale J, Cairncross JG, Sevick RJ, Kelly JJP.
J Neurosurg. 2018 Jul;129(1):19-26.

Functional Connectivity in Frontoparietal Network: Indicator of Preoperative Cognitive Function and Cognitive Outcome Following Surgery in Patients with Glioma.
Lang S, Gaxiola-Valdez I, Opoku-Darko M, Partlo LA, Goodyear BG, Kelly JJP, Federico P.
World Neurosurg. 2017 Sep;105:913-922.e2.

Assessment of Cognitive, Emotional, and Motor Domains in Patients with Diffuse Gliomas Using the National Institutes of Health Toolbox Battery.
Lang S, Cadeaux M, Opoku-Darko M, Gaxiola-Valdez I, Partlo LA, Goodyear BG, Federico P, Kelly J.
World Neurosurg. 2017 Mar;99:448-456.

Tumor endothelial marker 8 overexpression in breast cancer cells enhances tumor growth and metastasis.
Opoku-Darko M, Yuen C, Gratton K, Sampson E, Bathe OF.
Cancer Invest. 2011 Dec;29(10):676-82

Clinical Trials

Clinicaltrials.gov >>


English and Akan


  • Altru 1300 Columbia

    (formerly Altru Rehabilitation Center) 1300 S. Columbia Rd. Grand Forks, ND 58201

    Main: 701.780.5000